Stable protein, unstable plaque?

vowel quality in persian: stable or unstable?

this paper addresses the validity of two hypotheses concerning changes of vowel quality in persian. the theory of centralization claims that there is a strong correlation between vowel duration and vowel quality. as vowel duration is shortened in unstressed contexts, the size of the vowel inventory reduces toward the center, leading to considerable overlap between different categories and a red...

How to stabilize unstable plaque.

Association studies and epidemiological observations have shown that high plasma levels of high-density lipoprotein-cholesterol (HDL-C) provide cardiovascular protection. The anti-atherosclerosis activity of HDL is multifaceted and may include anti-thrombotic, antioxidative, and anti-inflammatory mechanisms. However, reverse cholesterol transport through which cholesterol is removed from tissue...

The Unstable Carotid Artery Plaque

Molecular MRI of murine atherosclerotic plaque targeting NGAL: a protein associated with unstable human plaque characteristics.

AIMS Neutrophil gelatinase-associated lipocalin (NGAL) is an effector molecule of the innate immune system. One of its actions is the prolongation of matrix metalloproteinase-9 (MMP-9) activity by the formation of a degradation-resistant NGAL/MMP-9 complex. We studied NGAL in human atherosclerotic lesions and we examined whether NGAL could act as a target for molecular imaging of atheroscleroti...

Angiographic plaque complexity: the tip of the unstable plaque iceberg.

Coronary plaque rupture is implicated in the pathogenesis of the acute coronary syndromes (1–9). Complex lesion morphology is the angiographic hallmark of these unstable ischemic syndromes, and it correlates with pathologic evidence of plaque rupture (7–9). In this issue of the Journal, Kerensky et al. (10) describe the angiographic patterns of plaque instability in 350 patients with nontransmu...